Carboxylic acids and derivatives
Apexbio Technology LLC Proanthocyanidin B1 20315-25-7 5mg
Proanthocyanidin B1 (CAS 20315-25-7) is a naturally occurring flavonoid compound isolated from the inner bark of Betula pubescens Ehrh hypophloedes As a dimeric proanthocyanidin it is recognized for its antioxidant properties exerting activity through the scavenging of free radicals and modulation of oxidative stress pathways Proanthocyanidin B1 is frequently employed in biomedical research to investigate its effects on cellular oxidative status inflammatory responses and its potential protective roles in models of degenerative diseases The compound is typically stored in airtight containers under cool dry conditions to maintain stability
Medchemexpress LLC Sumanirole maleate (U-95666E; PNU-95666E) | 179386-44-8 | 99.8% | C15H17N3O5 | 100 MG
Sumanirole maleate (U-95666E; PNU-95666E) is a highly selective D2 receptor full agonist with an ED50 of about 46 nM. It plays an important role in the research of Parkinson's disease and restless leg syndrome.
- Highly selective D2 receptor full agonist
- ED50 of about 46 nM
- Valuable tool compound for basic research
- Identifies neurobiological mechanisms based on dopamine D2-linked mechanism of action
Cayman Chemical PLC thioPIP2 sodium salt
A novel, chromogenic substrate for PLC; hydrolysis by PLC yields a free thiol which reacts with chromogenic reagents such as DTNB (Ellman’s reagent) to allow quantitation of PLC activity
Apexbio Technology LLC Moxalactam (sodium salt) 64953-12-4 10mM (in 1mL DMSO)
Moxalactam sodium salt (CAS 64953-12-4) is a small-molecule -lactam antibiotic belonging to the oxacephem subclass It is designed to inhibit bacterial cell wall biosynthesis by targeting penicillin-binding proteins (PBPs) Moxalactam sodium salt exerts its biological activity by interfering with PBPs thereby preventing cell wall synthesis In in vitro studies Moxalactam sodium salt demonstrates broad-spectrum inhibition of various Gram-positive Gram-negative and anaerobic bacteria including Klebsiella pneumoniae Escherichia coli Haemophilus influenzae and Neisseria gonorrhoeae Typical MIC values for susceptible organisms are generally in the low microgram-per-milliliter range Based on these pharmacological properties Moxalactam sodium salt holds research potential in antibacterial susceptibility assays studies on antibiotic resistance mechanisms and investigations of bacterial cell-wall synthesis pathways
eMolecules Medchem Express / Bicyclol / 5mg / 446273275 / HY-B0766 / / 118159-48-1 / MFCD00889471 / 390.344 / C19H18O9
Medchem Express / Bicyclol / 5mg / 446273275 / HY-B0766 / / 118159-48-1 / MFCD00889471 / 390.344 / C19H18O9
Cayman Chemical Thioperamide maleate
A selective histamine H3 receptor antagonist that crosses the blood-brain barrier; binds to rat cerebral cortical cells in vitro with a pKi value of 8.4
Selleck Chemical LLC Sulforhodamine B sodium salt
Sulforhodamine B (SRB Acid Red 52 Kiton Red 620) sodium salt is a protein-specific fluorescent dye that is utilized to quantitate cell expansion growth and migration
Apexbio Technology LLC (S)-Naproxen,25g CAS# 22204-53-1
(S)-Naproxen is a non-selective COX inhibitor [1,2].Cyclooxygenase (COX) is the key enzyme required for the conversion of arachidonic acid to prostaglandins. Cyclooxygenase enzymes have been involved in diverse physiological situations and disease processes ranging from inflammation to cancer. Until now, two cyclooxygenase isoforms have been identified, COX-1 and COX-2. The COX-1 enzyme is produced constitutively (i.e., gastric mucosa) and COX-2 is inducible (i.e., sites of inflammation) [3]. (S)-Naproxen inhibited the activity of human recombinant COX-1 and -2 with the IC50 values of 0.6-4.8 μM and 2.0-28.4 μM, respectively [1]. (S)-naproxen bound tightly to Aβfibrils with the Ki value of 5.70 ± 1.31 nM against [18F]FDDNP [2]. Pretreatment with (S)-naproxen significantly reduced the specific binding of [18F]FDDNP to regions of gray matter with SPs in AD specimens [4]. Other sizes are also available. Please inqury us for quote.
Selleck Chemical LLC Saccharin sodium salt hydrate
Saccharin (O-Sulfobenzimide O-Benzoic sulfimide Saccharimide) is an artificial sweetener with effectively no food energy
Cayman Chemical Pravastatin sodium salt
A potent HMG-CoA reductase inhibitor (Ki = 2.3 nM); reduces total plasma cholesterol levels by 29% in dogs at 20 mg/kg per day for five weeks
Apexbio Technology LLC Flupirtine maleate 75507-68-5 100mg
Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
Pfanstiehl Inc Dramamine Active EDGT (D-135) 5kg pack API, active pharmaceutical ingredient- CAS: 523-87-5
Dramamine Active EDGT (D-135) 5kg pack API, active pharmaceutical ingredient- CAS: 523-87-5
Apexbio Technology LLC Cefoxitin (sodium salt) 33564-30-6 250mg
Cefoxitin sodium salt (CAS 33564-30-6) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit PBPs thereby interfering with bacterial cell wall synthesis and peptidoglycan cross-linking Cefoxitin sodium salt exerts its biological activity primarily through inhibition of cell wall synthesis by binding to PBPs In in vitro enzymatic assays Cefoxitin sodium salt demonstrates inhibitory activity against various gram-positive and gram-negative bacteria with previously reported IC50 values in the low micromolar range due to its resistance to certain beta-lactamases including AmpC -lactamases Based on these pharmacological properties Cefoxitin sodium salt holds research potential in investigations of bacterial resistance mechanisms antimicrobial sensitivity profiling and beta-lactamase enzyme kinetics